a universal protein array system for quantitative detection of protein-protein, body weight and body mass index on patients with hypercholesterolemia: a systematic review and meta-analysis., Cotranslational protein-RNA associations predict protein-protein interactions., Diagnostic performance of circulating exosomes in human cancer: A meta-analysis., DNA, Effects of plant protein and animal protein on lipid profile, Gene, Predicting protein-protein binding sites in membrane proteins., protein-DNA, protein-RNA and protein-ligand interactions., Proteins, Reagents, RNA, The functions of CAP superfamily proteins in mammalian fertility and disease., UPA

A Difluoroalkylation Reagent for Organocatalytic Vinylogous Nitroaldol

A spot check for willpower of residual TBA ranges in  F-radiotracers for human use utilizing Dragendorff reagent


When using [18F]tetrabutylammonium fluoride ([18F]TBAF) within the synthesis of 18F-labeled radiotracers for scientific positron emission tomography (PET) imaging, it’s essential to substantiate that residual TBA ranges in formulated doses don’t exceed established specs (≤2.6 mg per affected person dose).

Historically this has been completed utilizing HPLC, however that is time consuming for short-lived PET radiotracers and restricted by the necessity for costly gear. This motivated us to introduce a TLC spot check for figuring out residual TBA, and we’ve got developed a brand new methodology which employs the Dragendorff reagent. Herein we report particulars of the TLC methodology and use it to quantify residual TBA in several formulations of 6-[18F]fluoro-DOPA. read more